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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3b2a42b945e6b5dbbd77fca057e681ad6d45b1f499c898d90451c1e5493d86ff' 
  AND token = 'I4x5cQV2uHwOhFuFrTbzmNLs/TpivPWrHQ7XV3eyIeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}