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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e8f27986e32f418a12a43e49a0fc282390ac7b42c3ad80b7561663ca334af7e' 
  AND token = '2q+YiDh1AHwgy6g+PPn5R4hyEeIvn5MTFrsFx2R0BG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}