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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '04a056788392e5c63f29d8030dcd895e67bc0125c9b47aedfa34affa26f8be17' 
  AND token = 'DMtWL70Y6SNKEjuwsnsRAgsLSxF/ap7rSrcC9Nf1Qj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}