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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5df0f5e510e95a14e121a881f27499c7b306505491db4775b1ece48565957b5e' 
  AND token = 'ccUf4+IAzWL862oEPC+nCkE1bt4MVNXzlkM+SoGpyBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}