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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e42e8ae01aa284d4441504dc4a5a176b741bd727145297d458bafab3da33cfd4' 
  AND token = 'Pa0bWmTBsnc4nJjlvQO3gM14jKYL+WNsjuipzYcpgS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}