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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7ed5ff75ec0b95ce3e880d98beb71745c9331210f425b8b13ca2e06b6d011203' 
  AND token = 'VrTbeROYOgvQ5HmrYESVNlswJ0hTJV6/6Lre3+Mi8wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}