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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5cde01711fb3093a10a97aa86e898d697f2326dd12df4b7a4daf912e486ed669' 
  AND token = 'Sx/RS95lacCm8k/16pBTiNC904QfxFWz7TLRQOWdZ64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}