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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c36b417d9e5bfd08c50d916d8d3950657e3fc8a51fc8bac993f53143f3dddfe' 
  AND token = 'nlwXtlagNuuipgEaZCs2q18To874FgiFgc1qwUdgpu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}