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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4402f595addbd4c243c1be21607b88a3bc12145a1e871b64b80f935be41fa528' 
  AND token = 'qrI+LlNK3m7qEocmpVdDmYbqXtyzQoYr4vBe/c2drvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}