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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2180a5df8ced93418e9e8fb80d1529a7712b7e7ff56201fca9b5e0749dfc9014' 
  AND token = 'Wu1OR78d6d6UZ24daID+CzdaztXhP1tKKDVh3YFJDig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}