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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80e738a2cb283fbd09286688966b379cedc21ef04845897007ae482663b64ae2' 
  AND token = 'f/BDdN6GtEIq1OgcSeahm1zxiWH3A+8mdNw2gidue0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}