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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8043a649a3160fbf358d9240cc123f52275b23ed5c74ed732e7287f68ca73f27' 
  AND token = 'yivTtHrP6xR1ZrxO4TyoOnJ1qUtwh2b4bNd6EkcI/bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}