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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4edc4fbd64db5db62b488bad7bda67125fe9aef89bb90590d368ebc0928a41e9' 
  AND token = 'b/xMel67Op/ZBI4zLKsMsK/H16g8pBVHVaFamTpvH4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}