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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0129918f401aa69bc89c73ca3c76fde29a8c43bba5633d93c769c75348d09afa' 
  AND token = '+zDW+n5SbF492/qXWQ9k+OA2XqG89v7SSUsXDz5hMeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}