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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f6fd0d514b846d11a637e71ea6e31113211eb5cba9bd0e1beda6c67e2b1bc130' 
  AND token = 'akV+ANQ00hvnOgUqJPahaRuzzswNp9qThW+Sqyh4rHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}