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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5682761a8c7e563747ab96757ff7fc9ccbd63a8da9703061c67fc134477518f9' 
  AND token = 'VIt1Zd4xudIDlDhXjXAIJwqmfIVOO7bame4f9paXA/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}