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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'af781721f3cf385485559af10f27ea81adba10a88947b918d23bf2ba756fab2e' 
  AND token = 'wR6wp5UEL0BOcwWE1mzJx+tPo/D+SMgd348EpiJPTFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}