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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21caf151b261fbefe19062170081086eac390ea9cc63e93cad2fcd8f6cdab2d6' 
  AND token = 'NDXjZmb3j2/x/LUTkXZIDJ2UOjHhfN+cGApZ+oYMBws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}