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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '152a8bdf2646fef2abab304ed7bed711133b54eaeede8d5cb14d16b985c7138f' 
  AND token = 'VPWBtmA8Tdv2Z8/cxOLXSAgM1pLNLB6EDcrN4bhmW4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}