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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4d649031bd3339c55c43cb14bcac7182f15eec31beff93a46c9814ac344e87df' 
  AND token = 'ROA4Pet3+3F/9utPybDnRv5p0MKr/NpMIAlwldY7wuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}