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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6223f3705ee16ee67a500021e2ad25a966ffec0ebe23dc121264c6aad0c81b5c' 
  AND token = 'HhMeMxlAKpMP4Y4+or13vSyQhCN2EJ7vyk2cCDYsSbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}