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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd4c5ce4e1280d26feb6ec1c4e485d77bf29ecf53f91a71ee12ada37f53bf5920' 
  AND token = 'hYgA+d3xhTyKdRWFSn4ASIGPoYb2RkTJcs1JmoSXp1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}