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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4b1eaa6c052cbbbbd9956e647190a274e3cba1ccd8c970367249e7881d642152' 
  AND token = 'PVyUDsHpzSGkNQ8X7p+eeW1MtXdf+oIH/TxG8j/xaAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}