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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2c4dd6e51ef321faeeeb46c329c7adcbd50d49997f1096896a8205e4baaac4db' 
  AND token = 'TlMzBOqrcs0Cat+H3cgYUZgNOknUyMJJ8Vrf0kqZvfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}