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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '781f8e33630f9558fdd9c5d3413206d8e80f1e167f9af5c4c4fb1a1be312a157' 
  AND token = 'ArPvIsnG/s6oqsG/q45geZg4VaEWT8n1/EJzZtnb2r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}