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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8dfad6f07dc7414f55c901aa097e93bc289f6083b44f1440645df01909eda4c8' 
  AND token = 'E8UEnVYnEEUxbMX1s8ZTzJXicx0P8NROyA6FmYSkaYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}