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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e435a770fac469577dab9d883a83d027bd302968a8ecc288ee4531c1e7435b5' 
  AND token = '0MDa5NUS8W/1lRLQxuOE9LE7FLgoVTuH9shZ+hUXQpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}