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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21053440c2e93ee07a195e43a4ee6196356e394d4dba7184182352c1ae4fa54a' 
  AND token = 'HQ58vlBs0Y14AYdohKg1QUr/i7jjT5FRXoTF/PXBUZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}