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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '86278c9b5cb521a6e221105f91012ace6a0bf05f042c69863c7ba3fab1ae518c' 
  AND token = 'qZoL44ilS+gyTRQnQM4RmEpHoMtIFGuKl5YJPltl3io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}