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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fec5df0de70c3b28e35351a81a1b5de948f10fe1ca0021f0947e47bd43105369' 
  AND token = 'XkcB3BIxjSm750fpVKlIkBzHG0NyA0vIxsRZfdDVUS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}