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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4b3cb0a7e38463a09c464834a9f37c39980783f75a734b5e44bc657aaa550bc5' 
  AND token = '4umwtRdoiuF1M9oMgYQGWu0DKT8PTI294TMzfz13qkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}