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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'debbacbf7f6715d0681fba4c801bf1326429bee1f01185c661cecdfef864b308' 
  AND token = 'ylwXwIosPGw+HtMoxUwnMrX6j/+zTI+57nyWPhlaD38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}