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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a48a591cdbd8a9e6a2f7427c01b7eaada080e2a73187fbd54491e79f1b86442f' 
  AND token = 'EElxxWJzHv1NvtSQuOYs5+1aO4CROyPHCnLuFNO1nGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}