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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f75956c40144786ab415c2c9defb1fb18fff683700cbf42c90403a4e541c3f78' 
  AND token = '+yQJ71SLuQnir8C7iQCbuUP6eVZyTiNV9nTl7Cx+MP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}