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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5edf77468bf1a6227f6ac6c81ffe5315dad5f3d3d87e16e2d7cf5a54336a4e27' 
  AND token = '8S7/gtAy6psNAGhdSirPKc+N5PT6TJsvYhx9+G01EdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}