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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f9a870047491210fb7acec05410b61a9fe4c967995e8e0a596f9f31102c4d783' 
  AND token = 'ZiV1RGQF4ChYJ0lOc5AdZ9P3yj2Pbc2lWHRLVD4IWxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}