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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '211a9afc7cf3a451c476e936f14129725596ec292f148499397c71d2c850b59c' 
  AND token = 'KeBLR9NPSFhxG2zrL4/SDTIO1PDh5h0aZ98vLKKrzvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}