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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '545e473c9eb5e69742f191ab5a9d9507a1bf59314ecae881052dc51f26edf171' 
  AND token = '16pyk3YdTZRV+ZWR+HKncHLUCMu2r+dIMSix+oIgSCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}