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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8dde8b03c920917677d5acfcb2a65e6839827b015c48d9bbd3cd0cb7d878ffe6' 
  AND token = 'C/xQYktXys5Csped7pyeM15cpDjRUToeqnTrjhZnrCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}