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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fe454f1b46ac008581ae08c7b30b5a13157d658430bb571ce140bad5992c8e94' 
  AND token = 'uClSjohLHUTQMTI86QMoAtEBJgc436VAZA04h+mjOTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}