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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '844cdfaefb2e94f104f65a6ebb8c9a9389ddab33cfb3d8a35453d756bc837868' 
  AND token = 'ZX8uOpgmwr0yb5e534NmcuoEr7weZZyqvF0aYEgIodk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}