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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2d29f34f812dad3d3a7dbf2d0234d360df35feb512efb9160c866ae3debe4a1' 
  AND token = 'EN8bgpd5qGyU1rdu/vBxi2xmrHM+aXqWbNMBmnyCQj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}