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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a103483b7aa9db6018345bd82f7fa37f389d96b6b682e6399341d43bd20aa378' 
  AND token = 'C1EL87+qtyQnii/xm6x1rlXPPQopkdo3V627ebhXkww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}