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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '24eef350536fc0fab51b62286a8adec2c62d1264d8cc4d511c16f4833acc8045' 
  AND token = 'o6kseToxYU3pMscZm+25UoBtUsD/K6LxbX+j7Hzy8aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}