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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49d90688bbc4080ab93b3ea6d3da1c8b60f6b083206e03bb74fc1d436e1b2ea4' 
  AND token = 'IaDdhKsNUhc+zWU5xQOwA7vQcWKyQt/eDWJGZKldnN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}