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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c2afd9c1e68cb7def007c27d924c7a3078cb0b94f4609b943b394bf77864a1d6' 
  AND token = 'UblAGireYXh7ki1o8e5BpzwFZ4ztBnse166kEy536+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}