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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ac006520254531b056836730346beeee6a3f547e2a8eb95149a1602617f89401' 
  AND token = 'Ft4Qqvuy+Qvv4InTirNvD1IRTCKxKfis4lzBDf9Nxj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}