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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e4f56d8ac92aa4b5c733832fef8c60de3138493a74e2018689fd18006e8d0996' 
  AND token = 'd1STsFNB/sV4USFx4DFZYAkagQKQ3Slb0tQQqAhm8XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}