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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45f182d6c16d40134bff01c2cb51aa57c2eef08888cc16c62cfbd04b3980693e' 
  AND token = 'Fxrp4vfBWvcIaFMf9Eh8A3WA8+JFYEXWeAKWhboTPMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}