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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b887155283a87123a940ede365644675fd583d8dfd17f6d88b45a5cbe6c9b491' 
  AND token = 'RcO7Qw3t22Yinj4B4O3E+JijuquTjNd1VB7eSTiWqpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}